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2021年9月20日

生命システム医学専攻4年Mariana Almeidaさんと柴垣翔平研究員の論文がBBRC誌にアクセプトされました。
An inhibitory immunoreceptor, Allergin-1, suppresses FITC-induced type 2 contact hypersensitivity.
Almeida M, Shibagaki S, Tahara-Hanaoka S, Shibayama S, Shibuya A.  
BBRC, in press

2021年9月15日

小田ちぐさ助教の論文がScience Immunology誌にアクセプトされました。
CD300a blockade enhances efferocytosis by infiltrating myeloid cells and ameliorates neuronal deficit after ischemic stroke
Nakahashi-Oda C, Fujiyama S, Nakazawa Y, Kanemaru K, Wang Y, Lyu W, Shichita T, Kitaura J, Abe F, Shibuya A.  
Sicence Immunol, in press

2021年5月18日

本研究室とTNAX biopharma株式会社との共同研究成果がプレスリリースされました。
https://www.tsukuba.ac.jp/journal/medicine-health/20210518160000.html

2021年4月23日

飯島綾菜さん（HBP2年）、金丸和正助教の論文がBBRCにアクセプトされました。
Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells.
Iijima A, Kanemaru K, Wang Y, Nabekura T, Nakamura Y, Fujisawa Y, Mori D, Ohmuraya M, Yamasaki S, Tahara-Hanaoka S, Shibuya A.  
BBRC, 561:101-105, 2021

2021年4月23日

西山奈菜子さん（生命システム2年）が、日本免疫学会「きぼう」プロジェクト（岸本忠三・若手研究者育成事業）免疫学博士課程支援に採択されました。

2021年4月21日

佐藤和貴助教の筆頭論文がPNAS誌にアクセプトされました。
DNAM-1 regulates Foxp3 expression in regulatory T cells by interfering with TIGIT under inflammatory conditions.
Sato K, Yamashita-Kanemaru Y, Abe F, Murata R, Nakamura-Shinya Y, Kanemaru K, Muratani M, Veillette A, Goto M, Ito M, Shibuya A, Shibuya K.
Proc Natl Acad Sci USA, 118(21):e2021309118, 2021

2021年4月8日

渋谷和子准教授が令和2年度Best teacher's awardを受賞しました。今回で16年連続になります。

2021年3月25日

生命システム医学専攻4年奥村元紀君が学位授与式において、人間総合科学研究科長賞および医学優秀論文賞を受賞しました。

2021年3月2日

生命システム医学専攻4年奥村元紀君が第29回東京免疫フォーラムで研究奨励賞を受賞しました。

2021年3月1日

金丸由美さん筆頭論文がMonoclonal Antibodies in Immunodiagnosis and Immunotherapy誌にアクセプトされました。
Suppression of Th1 and Th17 proinflammatory cytokines and upregulation of Foxp3 expression by a humanized anti-DNAM-1 monoclonal antibody.
Yamashita-Kanemaru Y, Oh-oka K, Abe F, Shibuya K, Shibuya A.
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 40(2):52-59, 2021

	DNAM-1 regulates Foxp3 expression in regulatory T cells by interfering with TIGIT under inflammatory conditions. Sato K et. al. Proc Natl Acad Sci USA 2021 Abstract (PubMed)
	Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells. Okumura G et. al. J Exp Med 2020 Abstract (PubMed)
	Type 1 innate lymphoid cells protect mice from acute liver injury via interferon-g secretion for upregulating Bcl-xL expression in hepatocytes. Nabekura T et. al. Immunity 2020 Abstract (PubMed)
	Clec10a regulates mite-induced dermatitis. Kanemaru K et. al. Science Immunology 2019 Abstract (PubMed)
	Autonomous regulation of IgE-mediated mast cell degranulation and immediate hypersensitivity reaction by an inhibitory receptor CD300a. Wang Y et. al. J Allergy and Clin Immunology 2019 Abstract (PubMed)
	Marginal zone B cells exacerbate endotoxic shock via interleukin-6 secretion induced by Fcα/μR-coupled TLR4 signalling. Honda S et. al. Nature Communications 2016 Abstract (PubMed)
	Apoptotic epithelial cells control the abundance of Treg cells at barrier surfaces. Nakahashi-Oda C et. al. Nature Immunology 2016 Abstract (PubMed)
	Immune regulation by Fcα/μ receptor (CD351) on marginal zone B cells and follicular dendritic cells. Shibuya A et. al. Immunological Reviews 2015 Abstract (PubMed)
	Toll-like receptor 4 and MAIR-II/CLM-4/LMIR2 immunoreceptor regulate VLA-4-mediated inflammatory monocyte migration. Totsuka N et. al. Nature Communications 2014 Abstract (PubMed)
	Costimulatory Molecule DNAM-1 Is Essential for Optimal Differentiation of Memory Natural Killer Cells during Mouse Cytomegalovirus Infection. Nabekura T et. al. Immunity 2014 Abstract (PubMed)
	Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE2. Kim Y et. al. Cell Host & Microbe 2014 Abstract (PubMed)
	Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor. Nakahashi-Oda C et. al. Journal of Experimental Medicine 2012 Abstract (PubMed)
	The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses. Nakano-Yokomizo T et. al. Journal of Experimental Medicine 2011 Abstract (PubMed)
	Critical role of DNAX accessory molecule-1 (DNAM-1) in the development of acute graft-versus-host disease in mice. Nabekura T et. al. Proc Natl Acad Sci USA 2010 Abstract (PubMed)
	An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions. Hitomi K et. al. Nature Immunology 2010 Abstract (PubMed)
	Enhanced humoral immune responses against T-independent antigens in Fcα/μR-deficient mice. Honda S et. al. Proc Natl Acad Sci USA 2009 Abstract (PubMed)
	Accelerated tumor growth in mice deficient in DNAM-1 receptor. Iguchi-Manaka A et. al. Journal of Experimental Medicine 2008 Abstract (PubMed)
	Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor. Tahara-Hanaoka S et. al. Blood 2006 Abstract (PubMed)
	Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation. Yotsumoto K et. al. Journal of Experimental Medicine 2003 Abstract (PubMed)
	CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. Shibuya K et. al. Journal of Experimental Medicine 2003 Abstract (PubMed)
	Fcα/μ receptor mediates endocytosis of IgM-coated microbes Shibuya A et. al. Nature Immunology 2000 Abstract (PubMed)